I once had a gay friend of mine chuckle and tell me, "What, you were surprised when he dropped that purse out of his mouth?"
I had been surprised when the burly, manly fellow before me had said, in a high, girly voice, "Oh mYYY GAAAWD, Look at his butt!"
I will always remember the expression my friend used, for it seems to me a pitch-perfect description of what I had observed.
What the fuck, over? Is another rather good expression, but imprecise by comparison.
Both apply to this, rather odd video: